The Frascati National Laboratories are located 30 Km Southeast of Rome, near the town of Frascati. 

Detailed Local Area Map
[including Frascati down-town, Villa Mercede (School Hotel) and INFN Laboratories]

All the information about transportation to/from LNF can be found here.

Airplane connections:

From Leonardo da Vinci airport in Fiumcino (FCO), you can reach LNF either by train or by car. The fastest way is to catch a taxi, which will take you to LNF in about 40 minutes. Taxis are available at the airport or could be reserved from the secretariat upon request. If you plan to rent a car, instructions to reach LNF can be found on the laboratory web page (click here).

Train connections:

From Fiumicino airport you can reach Frascati through Rome Termini railroad station. Trains for Termini leave the airport every half an hour, starting at 6:37 and up to 23:37. Once in Termini station you can reach the town of Frascati, using the Rome-Frascati line. From Frascati train station Villa Mercede and most of the hotels can be reached on foot or by a short taxi ride. Upon request, Hotel Villa Mercede will provide transportation from the Frascati train station to the hotel. If you wish to arrive directly to LNF from Rome, you can take the regional train Roma-Frosinone-Cassino and get off at Tor Vergata station. Beware that not all the trains stop in Tor Vergata. Check this before boarding (see also the Spring School Web Page,  How to reach the LNF ). Upon exiting the station in Tor Vergata, the laboratories are located 200 meters uphill, on the left hand side along Via Enrico Fermi (state your name at the interphone at the small green gate). Please notice that the Lab is not close to the hotels .